Skip to content Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic condition characterised by insulin resistance, impaired β-cell function, and the failure to regulate glucose, leading to sustained hyperglycemia (Baars, Fondevila, Meijnikman, & Nieuwdorp, 2024). Unlike Type 1 Diabetes, which is primarily autoimmune, T2DM is progressive but strongly influenced by lifestyle and metabolic factors—making it preventable and, in many cases, reversible. The magnitude of the problem is significant: 537 million adults worldwide currently live with diabetes, and up to 95% of these cases are Type 2 (IDF, 2021).
Conventional medicine has achieved important progress in monitoring and treatment, particularly through biomarkers such as HbA1c, which remains the gold standard for assessing long-term glycemic control. However, HbA1c and similar measures (e.g., fasting glucose) often detect dysfunction only at later stages of the disease (Kaiafa et al., 2021; Masoodian et al., 2023). This limitation underscores the need for strategies that go beyond symptom suppression.
Functional medicine provides such an approach by targeting the root causes of T2DM. Rather than focusing solely on blood glucose levels, it integrates nutrition, sleep, physical activity, gut health, oxidative stress management, and targeted supplementation into a patient-centred model (Chaney, Chaney, & Lambert, 2022). Research shows that dietary regimes such as the Mediterranean diet and low-glycemic eating patterns improve insulin sensitivity and lower oxidative stress (Pavlidou et al., 2023; Ni et al., 2022), while lifestyle practices like intermittent fasting enhance metabolic flexibility (Yuan et al., 2022).
This article aims to highlight that T2DM is not inevitably a life-long illness. Through multi-modal, evidence-informed interventions—including nutritional optimisation, lifestyle redesign, and the use of functional biomarkers such as fasting insulin, HOMA-IR, and continuous glucose monitoring—individuals can achieve meaningful improvement, and in many cases, reversal of their condition. The sections that follow build on this functional medicine framework, examining in detail how diet, sleep, exercise, gut health, oxidative stress reduction, and supplementation can be combined to restore metabolic balance.
At the core of reversing Type 2 Diabetes Mellitus (T2DM) are dietary patterns that reduce insulin resistance and systemic inflammation. Functional nutrition—often considered the dietary arm of functional medicine—uses food as a therapeutic tool to restore balance in the body. It emphasises whole foods, high fibre intake, and balanced macronutrients, with the goal of supporting underlying physiological processes rather than merely managing symptoms.
In practice, this means shifting the body away from glucose spikes toward metabolic stability. For example, replacing refined white rice with whole-grain brown rice or quinoa provides fibre and nutrients that slow glucose absorption, keeping blood sugar levels steadier.
Evidence shows that low-glycemic eating and the Mediterranean diet are especially effective in enhancing insulin sensitivity, lowering oxidative stress, and reducing diabetes risk (Ni et al., 2022; Pavlidou et al., 2023). Beyond macronutrient balance, food also directly influences the gut microbiome—a critical player in glucose regulation and inflammation (Baars et al., 2024).
Food is more than calories; it is information that communicates with the body, shaping insulin sensitivity, metabolic pathways, and gut health. In functional medicine, dietary choices are framed as therapeutic interventions (Muscogiuri et al., 2022).
Together, these foods form the backbone of a functional nutrition plan aimed at reversing insulin resistance and stabilising metabolism.
Just as certain foods heal, others accelerate dysfunction. Functional medicine highlights the importance of avoiding foods that trigger oxidative stress, inflammation, and glucose dysregulation:
Foods such as white breads, pastries, and sugary snacks create repeated glucose spikes leading to insulin resistance (Kaiafa et al., 2021).
Sugary drinks can disturb gut microbiota and cause systemic inflammation (Baars et al., 2024).
Canola and soybean-based oils for example are high in omega-6, which promote pro-inflammatory pathways (Caturano et al., 2023).
A staple of the fast food industry, they can damage endothelial function and increase visceral adiposity.
These potentially alter satiety signals and exacerbate oxidative stress.
Avoidance is not about strict calorie reduction but about eliminating dietary insults that perpetuate metabolic dysfunction.
The health impact of food also depends on how it is prepared. High-heat cooking methods such as frying, grilling, and broiling produce advanced glycation end-products (AGEs), compounds that worsen oxidative stress, insulin resistance, and diabetic complications (Caturano et al., 2023). Importantly, AGE formation does not require added sugars. Even foods such as chicken, beef, or potatoes generate significant AGEs when exposed to high temperatures in dry-heat conditions. This occurs because proteins and fats readily react through the Maillard reaction during grilling or deep-frying, resulting in AGE accumulation (Uribarri et al., 2010). Similarly, starchy foods like potatoes, when roasted or fried, also undergo chemical changes that increase their AGE content (Sharma et al., 2015).
In contrast, moist-heat cooking methods such as boiling, steaming, or poaching produce substantially fewer AGEs. Additional strategies such as reducing cooking time and marinating foods in acidic solutions (e.g., lemon juice or vinegar) have also been shown to limit AGE formation. This highlights that beyond the choice of ingredients, cooking methods themselves critically influence the dietary burden of AGEs and their potential role in T2DM progression.
Functional medicine emphasises cooking methods that minimise AGE formation while preserving nutrients, including:
• Steaming
• Boiling
• Slow cooking
• Baking at moderate temperatures
These approaches, when paired with antioxidant-rich foods (e.g., cruciferous vegetables, polyphenol-rich herbs), reduce metabolic load and support gut microbiome balance (Baars et al., 2024; Muscogiuri et al., 2022).
While diet forms the foundation of T2DM management, supplements can provide additional metabolic support when carefully selected and monitored. Clinical evidence suggests that several micronutrients and botanicals may enhance glycaemic control and reduce diabetes-related complications.
Chromium polynicotinate has been shown to improve glucose uptake and insulin sensitivity in muscle cells (Vincent, 2021).
Magnesium and Vitamin D supplementation enhances insulin receptor activity and β-cell function, with deficiencies in either nutrient linked to increased risk of T2DM (Gandhi et al., 2023).
Berberine, a plant alkaloid, has demonstrated effects comparable to metformin through activation of AMP-activated protein kinase (AMPK), modulation of the gut microbiota, and improvements in lipid metabolism (Sadeer & Mahomoodally, 2022).
Omega-3 fatty acids and alpha-lipoic acid (ALA) reduce systemic inflammation, oxidative stress, and symptoms of diabetic neuropathy (Kaiafa et al., 2021).
Coenzyme Q10 and N-acetylcysteine (NAC) help restore mitochondrial function and antioxidant defences, which are often impaired in chronic hyperglycemia (Masoodian et al., 2023).
Beyond these well-established agents, several botanicals have emerging evidence:
Gymnema sylvestre contains gymnemic acids that stimulate insulin release, regenerate β-cells, reduce intestinal glucose absorption, and decrease sugar cravings. Long-term supplementation has been associated with reductions in fasting blood glucose and HbA1c in patients with T2DM (Prakash & Devasagayam, 2022).
Bitter melon (Momordica charantia), particularly its active component charantin, mimics insulin activity and enhances glucose uptake via AMPK activation. Randomized controlled trials report improvements in fasting blood glucose, though findings on HbA1c are inconsistent (Rahman et al., 2021).
Cinnamon supplementation has been linked with reductions in fasting plasma glucose and improvements in insulin sensitivity. A 2022 meta-analysis highlighted modest benefits in glycaemic control, although results varied based on dose, duration, and type of cinnamon used (Shen et al., 2022).
Supplements are not substitutes for nutrition and exercise but act as synergistic supports, especially when combined with resistance training and continuous biomarker monitoring (Richter, 2021). In summary, food remains the most powerful therapeutic tool in reversing T2DM, but carefully chosen supplements—such as chromium, berberine, gymnema, bitter melon, and cinnamon—can accelerate metabolic improvements and enhance patient outcomes.
Monitoring the level of blood glucose and associated markers offers a platform that makes it feasible to manage and reverse Type 2 Diabetes Mellitus (T2DM). Of these, the most readily available measure is fasting glucose. Although traditional recommendations consider normal fasting glucose to be anything lower than 100 mg/dL (5.6 mmol/L), functional medicine distinguishes it as between 75 and 85 mg/dL (4.2 and 4.7 mmol/L), a point where there is still no clinical disease but where imbalances are just starting (Chaney, Chaney, & Lambert, 2022).
HbA1c is another marker commonly utilised, which reflects the average glucose over three months. The standard range of less than 5.7% is an indication of normoglycemia, but according to functional medicine, a safe range is 4.6-5.3% because even slight increases are associated with microvascular stress and disease over time (Kaiafa et al., 2021). HbA1c, despite its usefulness, does not reflect intraday glucose fluctuations, and thus, it is not a perfect single measurement.
Fasting insulin gives more insight into insulin sensitivity. Standard cut-offs (<25 1u/ml) do not always identify early insulin resistance, whereas functional medicine suggests a functional 2-61u/ml (how can it be 61 when cutoff mentioned earlier is 25 range detecting impaired insulin action when the glucose is still appearing to be normal (Muscogiuri et al., 2022). This is highly applicable, particularly in the detection of any latent metabolic dysfunction leading to diabetes.
The resistance can be measured more accurately with the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR). Of course, a reading of less than 3.0 is generally acceptable, but according to research, a level below 1.5 is a better indicator of protecting against cardiometabolic disease (Masoodian et al., 2023).
All of these biomarkers, when used in combination, enable clinicians to shift the focus of treatment away from symptom suppression to early diagnosis and targeted treatment. They are included via a functional medicine approach, not only as investigative aids but as facilitators that are used to adjust nutrition, exercise, and nutritional supplements regimens that can be used directly to reverse diabetes.
The utilisation of optimal biomarker ranges is one of the major tenets of functional medicine. The traditional medical practice is based on disease-related clinical cut-offs that diagnose disease after it develops. As an example, a fasting level of glucose below 100 mg/dL (5.6 mmol/L) is classified as normal, but those who lie on the upper end of this range have developed early insulin resistance and high HOMA-IR scores (Masoodian et al., 2023). Functional medicine, in turn, has superior values of the optimal levels of glucose (75 85 mg/dl, 4.2- 4.7 mmol/L) such that any malfunction might be pre-emptively diagnosed decades prior to the diagnosis of diabetes (Chaney, Chaney, and Lambert, 2022).
Similarly, HbA1c despite being very instrumental in the long-term glycemic trends is not without criticism. It is unable to capture fluctuations of glucose on a daily basis, or postprandial spikes that constitute components of endothelial harm and metabolic distress (Kaiafa et al., 2021). This does not mean that a patient with a classic HbA1c value is in the clear since he or she can still develop future and significant cardiometabolic problems. Functional medicine bridges this gap, where there is on-going glucose level monitoring (CGM) and fasting insulin protocol in order to determine the presence of pre-diabetes based insulin resistance which consequently results in the emergence of hyperglycemic manifestations.
It is also a prevention type approach to methodology. Early intervention will enable providers to introduce nutrition plans, intermittent fasting, and lifestyle redesign- which practice has demonstrated, can restore insulin responsiveness and reduce the overall burden of disease in the long term (Yuan et al., 2022; Goldberg et al., 2022). Also, one should keep in mind that the reduction of the dysbiosis and systemic inflammation at a younger age is not only conditional to the regularity of glucose levels but contributes to gut and immune stabilization (Baars et al., 2024).
In general, the change in the approach towards treating patients in health care with functional medicine involving scales of optimal versus conventional leads to the care-provision processes on a more proactive than a reactive setting, assigning patients not only the necessity to handle T2DM, but also the opportunity to overturn the course of the disease.
The commonly measured biomarkers, such as fasting glucose and HbA1c, are useful but ultimately insufficient snapshots of glycaemic control. HbA1c, for example, provides a three-month average but fails to capture day-to-day fluctuations or postprandial glucose peaks, which can silently contribute to vascular damage and metabolic overload (Kaiafa et al., 2021).
Continuous Glucose Monitoring (CGM) offers a promising and innovative solution to these limitations. By providing real-time feedback on glucose trends, CGM empowers individuals to identify dietary triggers, evaluate lifestyle interventions, and achieve tighter glycaemic control, making it a valuable tool in both the prevention and reversal of diabetes.
Using GMs gives patients real-time feedback on the effects food, exercise, stress, and sleep have on blood glucose and enables patients to make immediate decisions based on substantial amounts of data. CGM shows signs of dysfunction as they develop in the same way that traditional tests do not, creating feedback on glycemic variability as it happens and providing data on the causes of insulin resistance that could not be found in the traditional tests (Chaney, Chaney, & Lambert, 2022). As an example, the exercise during which the glucose enters the body stimulates GLUT4 transporters, which means strong behavioural feedback (Richter, 2021).
CGM enables patients to prevent prediabetic state and eventually to healthy levels by monitoring the effect food and lifestyle have upon their blood glucose levels individually. This personalised biofeedback brings a gap between abstract recommendations and real life, bringing responsibility and inspiration.
Besides CGM other markers such as (fasting insulin and HOMA-IR), which help to provide a view of the dynamism of metabolic health (Masoodian et al., 2023). In combination with other diet-related measures such as the Mediterranean or low-glycemic diet (Ni et al., 2022; Pavlidou et al., 2023), CGM allows detailed prioritising of treatments to regain insulin sensitivity.
In short, CGM heralds the new era of diabetes management as a future change in the way glucose monitoring can be used as a prevention tool, a management tool and even a reversal tool.
Sleep is not usually considered in the treatment of Type 2 Diabetes Mellitus (T2DM) even though it has a critical impact on the regulation of glucose and insulin sensitivity. Studies have found that insufficient quality and duration of sleep have a direct relationship with insulin resistance, regardless of their dietary routines and physical activity (Hashemipour et al., 2021). Violations in the sleep-wake cycle enhance nighttime cortisol concentration, which affects the ability to regulate glucose circulation and leads to uncontrolled insulin requirements in fasting (Masoodian et al., 2023). The disturbances over a lengthy period end up resulting in an increase in HbA1c despite the daytime glucose readings appearing to be well controlled (Kaiafa et al., 2021).
In functional medicine, restorative sleep is a priority as an intervention, given its effects on endocrine balance, oxidative stress, and even diversity in the gut microbiome, which play a significant role in T2DM pathophysiology (Baars et al., 2024; Caturano et al., 2023). It is recommended that, to achieve effective learning outcomes, individuals should get between 7 and 9 hours of good-quality sleep regularly with lifestyle choices that promote circadian compliance. Filtering out or avoiding blue light exposure for 2 hours before bedtime by wearing blue-blocking eye glasses maintains melatonin release that helps in sustaining metabolic restoration. Similarly, sleeping in total darkness using blackout curtains would eliminate the nocturnal arousals, whereas the minimisation of electromagnetic fields (EMF) exposure has been linked to deeper sleeping and hormone balance (Chaney, Chaney, & Lambert, 2022).
Following regular sleep-awake procedures is also very crucial because irregular schedules can dis-, and this process can raise the glycemic variability in circadian biology (Goldberg et al., 2022). The last of the triad of changes used in a non-pharmacological combination of strategies reveals quality sleep as the one that should be applied to reverse the worsening of insulin resistance.
In brief, prioritisation of sleep is not a sleeplike activity; it is an estimated metabolic strategy of stabilisation, decreasing of insulin resistance, and accelerating the remission of T2DM.
A combination of the most powerful non-drug-related remedies that backs to Type 2 Diabetes Mellitus (T2DM) is considered to be exercise. Physical exercise increases insulin sensitivity by promoting GLUT4 translocation at skeletal muscle on a cellular level such that glucose may enter the cells in the absence of insulin. This mechanism maximizes glycemic regulation and decreases the impact on the pancreas in case of excessively assuming amounts of insulin (Richter, 2021).
The comprehensive exercise program comprises of both aerobic and resistance training with a target set to 180min/week. Zone 2 training, brisk walking, cycling or swimming most days, focuses on fat burning and increases mitochondrial efficiency. This kind of moderate-intense physical activity has proven to boost insulin sensitivity and promote cardiovascular health into the future (Goldberg et al., 2022).
What is also very important is Zone 3/4 training, which includes high-intensity workouts and organised resistance training that should be conducted three to four times per week. Resistance training also has a very important role, namely, by increasing both the mass and the size of muscles, it also increases glycogen storage and the ability of cells to take in glucose, thereby directly reversing insulin resistance (Qadir et al., 2021). The increased lean body mass has systematically been associated with the reduced HOMA-IR, which once again emphasises its key role in reversing diabetes (Masoodian et al., 2023).
These effects are enhanced when a form of diet (e.g. a Mediterranean or low-glycemic diet (Ni et al., 2022; Pavlidou et al., 2023)) is added to exercise, along with the functional lifestyle interventions. It is important to note that exercise is not only able to lower glucose but also to lower overall inflammation and significant shifts in diverse population of gut microbiota, which could significantly enlist mechanisms of T2DM (Baars et al., 2024; Caturano et al., 2023).
Exercise, in short, is a non-complementary intervention, it is a basic one that re-educates the metabolic pathway restoring insulin sensitivity and accelerating resolution of T2DM.
Altogether, the gut is a focus in the T2DM pathophysiology over recent years. Dysbiosis of the bowel (i.e., the increasing or decreasing composition of the bowel in relation to the type of bacteria inhabiting it) has also been shown to workopsise the glucose turnover and support systemic inflammation, insulin resistance (Baars et al., 2024). Alteration of the bacteria diversity, including the destruction of the pro-beneficial strains of bacteria such as Akkermansia muciniphila, undermines the gut barrier integrity and ends in endotoxemia, which causes the low-grade inflammation characteristic of T2DM.
Antimicrobiotic interventions are therefore one of the functional medicine pillars of rights when it comes to the reversal of diabetes. On the one hand, there are the prebiotics, among which are chicory root, onions, and garlic, which nourish the positive bacteria, and on the other hand, there are the probiotics, i.e., Lactobacillus, Bifidobacterium, and Akkermansia, the direct reconstruction of the bacterial balance. Additionally, live cultures, including fermented milk products like kefir, fermented vegetables like fermented sauerkraut, fermented miso, and fermented kombucha, could provide the living cultures, in which case it could diversify the gut microbiome and enhance short-chain fatty acids (SCFA) synthesis to enhance insulin sensitivity (Bock et al., 2021). It is worthwhile noting that interference with the gut dysbiosis and the maintenance of glucose homeostasis by interfering chemicals such as the artificial sweeteners, emulsifiers, and the use of chronic medications should be avoided as they have been cited to disrupt both processes.
There are multiple benefits associated with gut healing. Optimized performance of microbiomes reduces systemic inflammation (Caturano et al., 2023), assists in the fortification of the gut barrier and condition to release increased amounts of GLP-1 hormone, which is critical to satiety and glycemic regulation. By combining it with exercise-induced GLUT4 activation (Richter, 2021) and proper biomarker monitoring, e.g., HbA1C (Kaiafa et al., 2021) and HOMA-IR (Masoodian et al., 2023), microbiome-focused treatments can increase the effects of lifestyle medicine.
One of the principles proposed here is that the promotion of gut health is not an accessory but a primary therapeutic avenue, which allows correcting metabolism as well as producing lasting control of T2DM.
Rather than viewing supplementation as a stand-alone therapy, functional medicine applies it in a targeted and personalised manner, complementing diet and lifestyle strategies. While the mechanisms of agents such as berberine, omega-3 fatty acids, alpha-lipoic acid, CoQ10, NAC, and zinc have been well-established (Sadeer & Mahomoodally, 2022; Caturano et al., 2023; Muscogiuri et al., 2022), their true clinical value lies in matching specific supplements to individual metabolic dysfunctions. For instance, berberine may be prioritised for patients with insulin resistance, omega-3 fatty acids for those with chronic systemic inflammation, and NAC or alpha-lipoic acid where oxidative stress predominates.
When combined with resistance training (Richter, 2021) and guided by biomarkers such as HbA1c (Kaiafa et al., 2021) and HOMA-IR (Masoodian et al., 2023), these supplements shift from being “add-ons” to becoming integral components of a holistic therapeutic plan. Thus, functional medicine recognises targeted supplementation not as a duplication of pharmacology, but as an instrument to optimise insulin action and restore metabolic resilience at the root of T2DM.
Lifestyle medicine is the decisive choice to reverse Type 2 Diabetes Mellitus (T2DM), as it is the actual habits that cause the insulin resistance. Physical activity with resistance training is the most potent intervention of all interventions. The Diabetes Prevention Program results demonstrate that lifestyle-based interventions are 58 per cent more effective in preventing diabetes than metformin (Goldberg et al., 2022). To a large extent, this significant impact is carried out through an increase in glucose disposal by processes such as GLUT4 translocation in skeletal muscle within the body to promote insulin sensitivity and glucose uptake (Richter, 2021).
Exercise is, however, more than good diabetes management. Stress on a long-term basis will lead to the rise in cortisol levels, as well as interfere with the circadian rhythm and worsen insulin resistance. Such functional interventions as heart rate variability (HRV), progressive muscle relaxation, and mindfulness meditation can decrease the systemic stress levels of a person, bringing a reduction in glucose control and well-being overall (Chaney, Chaney, and Lambert, 2022).
There is also a pressing need that behaviour change frameworks are implemented. Eventually the patients themselves will embrace the SMART goals, which means that they will strive to build lasting patterns, when it comes to eating, exercising and sleep. With accountability systems and longitudinal monitoring, such structures will encourage long-term compliance, which is critical as metabolic reversal is based on long-term compliance rather than a specific short-term intervention.
Lifestyle medicine and the optimisation of the diet (Pavlidou et al., 2023), restoration of the gut microbiome (Baars et al., 2024), along with subsequent monitoring of biomarkers such as HbA1c or fasting insulin (Kaiafa et al., 2021; Masoodian et al., 2023), can turn T2DM management into a reversal of its causes, instead of merely controlling its symptoms. This whole-person approach ultimately allows patients to not only reduce blood glucose but also recover metabolic resilience to experience lifelong health.
Through the advent of personalised medicine, treatment of T2DM will be transformed in terms of paradigm. Treatments that involve microbes are on the rise since the gut has been central to the regulation of glucose and inflammation (Baars et al., 2024).
Eventually, custom-made probiotics/ prebiotic treatment regimes to restore diversity and enhance insulin sensitivity can be incorporated. Moreover, personalised nutrition on a genetic basis and metabolomics basis may be valuable as well with a prescription of a specific diet and nutrition being more effective than broad generalizations.
There is AI-guided digital health tracking that integrates on an equal footing with it. With the combination of CGM and advanced analytics, the patient will be able to receive answers about diet, physical activity, and sleep timely. These technologies do not only simplify the biomarkers like HbA1c (Kaiafa et al., 2021): they also enable the patient to be engaged in his/her state of metabolic parameters. Collectively, these advancements indicate that precision, prevention, and personalisation would be the new definition of future T2DM care.
T2DM is a reversible condition when underlying conditions that cause it, such as insulin resistance, oxidative stress and gut dysbiosis, are eliminated, instead of merely suppressing hyperglycemia. Included in a functional medicine approach, which combines whole-food nutrition, high-intensity resistance exercise that induces GLUT4-mediated glucose uptake (Richter, 2021), improved sleep hygiene (Hashemipour et al., 2021), microbiome restoration, and targeted supplementation (Sadeer & Mahomoodally, 2022), a comprehensive model is presented to reverse the disease state in the long term.
The use of unique protocols has also proved to be highly effective as it ascertains individual patient health goals in a manner that cannot be measured by one-size-fits-all approaches (Chaney, Chaney, & Lambert, 2022).
In conclusion, there is a reason to assume that T2DM is no longer an invariable lifetime disease. By treating metabolism on a root level, one can regain their health, regain insulin sensitivity and maintain a good quality of life. Functional medicine can provide not only control, but empowerment to metabolic liberation.
Baars, D. P., Fondevila, M. F., Meijnikman, A. S., & Nieuwdorp, M. (2024). The central role of the gut microbiota in the pathophysiology and management of type 2 diabetes. Cell Host & Microbe, 32(8), 1280-1300.
Bock, P. M., Telo, G. H., Ramalho, R., Sbaraini, M., Leivas, G., Martins, A. F., & Schaan, B. D. (2021). The effect of probiotics, prebiotics or synbiotics on metabolic outcomes in individuals with diabetes: a systematic review and meta-analysis. Diabetologia, 64(1), 26-41.
Caturano, A., D’Angelo, M., Mormone, A., Russo, V., Mollica, M. P., Salvatore, T., … & Sasso, F. C. (2023). Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications. Current Issues in Molecular Biology, 45(8), 6651-6666.
Chaney, T., Chaney, S., & Lambert, J. (2022). The Use of Personalized Functional Medicine in the Management of Type 2 Diabetes: A Single-Center Retrospective Interventional Pre-Post Study. Alternative Therapies in Health & Medicine, 28(6).
Gandhi, S., Patel, M., & Joshi, A. (2023). Magnesium and vitamin D in type 2 diabetes: Implications for glycaemic control. Diabetes Research and Clinical Practice, 196, 110193. https://doi.org/10.1016/j.diabres.2023.110193
Goldberg, R. B., Orchard, T. J., Crandall, J. P., Boyko, E. J., Budoff, M., Dabelea, D., … & Diabetes Prevention Program Research Group*. (2022). Effects of long-term metformin and lifestyle interventions on cardiovascular events in the diabetes prevention program and its outcome study. Circulation, 145(22), 1632-1641.
Hashemipour, S., Ghorbani, A., Khashayar, A., & Olfati, H. (2021). Association of sleep quality with insulin resistance in obese or overweight subjects. Sleep Science, 14(S 01), 75-78.
Kaiafa, G., Veneti, S., Polychronopoulos, G., Pilalas, D., Daios, S., Kanellos, I., … & Savopoulos, C. (2021). Alpha-lipoic acid and diabetic neuropathy: A systematic review and meta-analysis. Nutrients, 13(12), 4407. https://doi.org/10.3390/nu13124407
Kaiafa, G., Veneti, S., Polychronopoulos, G., Pilalas, D., Daios, S., Kanellos, I., … & Savopoulos, C. (2021). Is HbA1c an ideal biomarker of well-controlled diabetes?. Postgraduate Medical Journal, 97(1148), 380-383.
Masoodian, S. M., Omidifar, A., Moradkhani, S., Asiabanha, M., & Khoshmirsafa, M. (2023). HOMA-IR mean values in healthy individuals: a population-based study in iranian subjects. Journal of Diabetes & Metabolic Disorders, 22(1), 219-224.
Masoodian, S., Nazari, M., & Hosseinzadeh, H. (2023). Coenzyme Q10 and N-acetylcysteine as mitochondrial protectors in diabetes: A review of mechanisms and clinical evidence. Frontiers in Endocrinology, 14, 1122334. https://doi.org/10.3389/fendo.2023.1122334
Muscogiuri, G., Barrea, L., Caprio, M., Ceriani, F., Chavez, A. O., El Ghoch, M., … & Colao, A. (2022). Nutritional guidelines for the management of insulin resistance. Critical reviews in food science and nutrition, 62(25), 6947-6960.
Ni, C., Jia, Q., Ding, G., Wu, X., & Yang, M. (2022). Low-glycemic index diets as an intervention in metabolic diseases: a systematic review and meta-analysis. Nutrients, 14(2), 307.
Pavlidou, E., Papadopoulou, S. K., Fasoulas, A., Papaliagkas, V., Alexatou, O., Chatzidimitriou, M., … & Giaginis, C. (2023). Diabesity and dietary interventions: Evaluating the impact of mediterranean diet and other types of diets on obesity and type 2 diabetes management. Nutrients, 16(1), 34.
Prakash, R., & Devasagayam, T. P. A. (2022). Gymnema sylvestre: Antidiabetic potential and molecular mechanisms. Phytomedicine, 95, 153894. https://doi.org/10.1016/j.phymed.2021.153894
Qadir, R., Sculthorpe, N. F., Todd, T., & Brown, E. C. (2021). Effectiveness of resistance training and associated program characteristics in patients at risk for type 2 diabetes: a systematic review and meta-analysis. Sports Medicine-Open, 7(1), 38.
Rahman, S., Khan, I., & Alam, M. (2021). Hypoglycaemic effects of Momordica charantia in type 2 diabetes: Evidence from clinical trials. Journal of Ethnopharmacology, 276, 114180. https://doi.org/10.1016/j.jep.2021.114180
Richter, E. A. (2021). Exercise, nutrition, and metabolic health: Synergistic effects in type 2 diabetes prevention and treatment. Diabetologia, 64(9), 1826–1839. https://doi.org/10.1007/s00125-021-05474-3
Richter, E. A. (2021). Is GLUT4 translocation the answer to exercise-stimulated muscle glucose uptake?. American Journal of Physiology-Endocrinology and Metabolism.
Sadeer, N. B., & Mahomoodally, M. F. (2022). Berberine in metabolic diseases: Clinical efficacy and mechanisms. Frontiers in Pharmacology, 13, 876542. https://doi.org/10.3389/fphar.2022.876542
Sadeer, N. B., & Mahomoodally, M. F. (2022). Nutraceuticals and Dietary Supplements: The Future Smart Foods to Hamper Diabetes Mellitus and Associated Complications. In Clinical Studies on Nutraceuticals and Dietary Supplements (pp. 155-174). CRC Press.
Shen, Y., Zhang, X., & Chen, L. (2022). Cinnamon supplementation and type 2 diabetes: A meta-analysis of randomized controlled trials. Complementary Therapies in Medicine, 68, 102849. https://doi.org/10.1016/j.ctim.2022.102849
Vincent, J. B. (2021). Chromium and type 2 diabetes: An update on mechanisms and clinical outcomes. Nutrients, 13(11), 3960. https://doi.org/10.3390/nu13113960
Yuan, X., Wang, J., Yang, S., Gao, M., Cao, L., Li, X., … & Sun, C. (2022). Effect of intermittent fasting diet on glucose and lipid metabolism and insulin resistance in patients with impaired glucose and lipid metabolism: a systematic review and meta‐analysis. International journal of endocrinology, 2022(1), 6999907.
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